Recent publications

Protracted renal clearance of fentanyl in persons with opioid use disorder

Summary: This study aimed to measure renal clearance of fentanyl in patients with opioid use disorder in our residential treatment program.

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Differences in availability and use of medications for opioid use disorder in residential treatment settings in the United States

Summary: This study analyzed the variance in the administration of medication for opioid use disorder among residential treatment facilities across the United States.

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Trends in first-time treatment admissions for older adults with alcohol use disorder: Availability of medical and specialty clinical services in hospital, residential, and outpatient facilities

Summary: Older adults seeking treatment for alcohol use disorder may need specialized care, including medication supported recovery. In some facilities, this type of treatment is not available.

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Association of sleep disturbance, chronic pain, opioid withdrawal

Summary: There is very little research on sleep disturbances and chronic pain in persons going through opioid withdrawal. This study will examine whether chronic pain worsens opioid withdrawal and sleep disturbances in persons with opioid use disorder.

Status: IRB Approved/Active

A grant-funded multi-site clinical trial to study the relationship among sleep, stress, emotion, drug craving and relapse in outpatient facilities

Summary: There is no published clinical research on the role of the orexin neurotransmitter system in opioid use disorder. This randomized-controlled trial will examine whether a dual-orexin receptor antagonist improves sleep, stress and relapse outcomes in persons in early recovery from opioid use disorder.

Status: IRB Approved/Active

Upcoming studies

Improving treatment quality metrics within Ashley

Summary: We are tracking patient outcomes across a number of indicators to assess the quality of treatment as well as our data collection strategy with Trac9. The program tracked in-program stress, mental health and craving data, as well as numerous quality of life indicators for up to one year following completion of our treatment programs. This data will not only improve our operations and treatment methodologies but will also be viable for academic research purposes.